Agenda - Thurs, Oct 10, 2024
8:15 am - 9:00 am
Registration and Breakfast
9:00 am - 9:10 am
Welcome Remarks
Daljit Matharu, Senior Scientist I, Medicinal Chemistry, Sanofi
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Roman Manetsch, Professor of Chemistry, Northeastern University
9:10 am - 10:30 am
Graduate Student / Postdoctoral Talks (4 x 20 min)
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Development of GABARAP-specific stapled and N-methylated peptide modulators of autophagy
Imani McDonald, Kritzer Lab, Tufts University
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In-situ supramolecular nanotubes for extrinsic lytic cancer cell death
Meihui Yi, Xu Lab, Brandeis University
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Enantioselective Radical Process for Amination of Enamines: Asymmetric Synthesis of Chiral a,β-Diamino Acid Derivatives
Zhenyu Zhu, Zhang Lab, Boston College
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Chemoenzymatic methods for characterizing epigenetic enzyme activity
Sam Whedon, Cole Lab, Harvard Medical School ​
10:30 am - 11:15 am
Coffee Break & Poster Session #1
11:15 am - 12:15 pm
Academic Keynote
Radical isomerization tools outside the confines of thermodynamics
Alison Wendlandt, Associate Professor of Chemistry, MIT
12:15 pm - 1:30 pm
Networking Lunch
1:30 pm - 2:30 pm
Graduate Student/Postdoctoral Talks (3 x 20 mins)
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Synthesis of Carbohydrate Mimics: As glmS Riboswitch Activators and Potential Antibiotics
Bjarne Jonas Silkenath, Raines Lab, MIT
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Catalyst- and Solvent-free Green Synthesis of Heterocyclic Building Blocks, Drug Candidates, APIs by High Hydrostatic Pressure
Valerie Wright, Torok Lab, UMass Boston
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Antibody bottlebrush prodrug conjugates (ABCs) as a new platform for targeted cancer therapy
Bin Liu, Johnson Lab, MIT
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2:30 pm - 3:15 pm
Coffee Break & Poster Session #2
3:15 pm - 3:55 pm
Graduate Student/Postdoctoral Talks (2 x 20 mins)
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Aminative Suzuki–Miyaura Coupling
Paul Onnuch, Liu Lab, Harvard University
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Synthesis of Modified Nucleotides for saRNA Applications: Electrochemical Installation of Fluorinated Motifs on Purines and Pyrimidines
Kaitlyn Corazzata, Schaus Lab, Boston University
3:55 pm - 4:55 pm
Industrial Keynote
Think Biologically, Act Chemically
Matthew LaMarche, Head of Integrated Drug Discovery, Sanofi
4:55 pm - 5:00 pm
Closing Remarks
Jason Tedrow, Head of Process Chemistry, Sanofi
5:00 pm - 6:30 pm
Networking Reception