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Agenda -  Thurs, Oct 10, 2024

8:15 am - 9:00 am

Registration and Breakfast

9:00 am - 9:10 am

Welcome Remarks

Daljit Matharu, Senior Scientist I, Medicinal Chemistry, Sanofi

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Roman Manetsch, Professor of Chemistry, Northeastern University 

9:10 am - 10:30 am

Graduate Student / Postdoctoral Talks (4 x 20 min)

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Development of GABARAP-specific stapled and N-methylated peptide modulators of autophagy 

Imani McDonald, Kritzer Lab, Tufts University 

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In-situ supramolecular nanotubes for extrinsic lytic cancer cell death

Meihui Yi, Xu Lab, Brandeis University 

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Enantioselective Radical Process for Amination of Enamines: Asymmetric Synthesis of Chiral a,β-Diamino Acid Derivatives

Zhenyu Zhu, Zhang Lab, Boston College 

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Chemoenzymatic methods for characterizing epigenetic enzyme activity

Sam Whedon, Cole Lab, Harvard Medical School â€‹

10:30 am - 11:15 am

Coffee Break & Poster Session #1

11:15 am - 12:15 pm

Academic Keynote

Radical isomerization tools outside the confines of thermodynamics

Alison Wendlandt, Associate Professor of Chemistry, MIT

12:15 pm - 1:30 pm

Networking Lunch

1:30 pm - 2:30 pm

Graduate Student/Postdoctoral Talks (3 x 20 mins)

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Synthesis of Carbohydrate Mimics: As glmS Riboswitch Activators and Potential Antibiotics

Bjarne Jonas Silkenath, Raines Lab, MIT 

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Catalyst- and Solvent-free Green Synthesis of Heterocyclic Building Blocks, Drug Candidates, APIs  by High Hydrostatic Pressure  

Valerie Wright, Torok Lab, UMass Boston

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Antibody bottlebrush prodrug conjugates (ABCs) as a new platform for targeted cancer therapy 

Bin Liu, Johnson Lab, MIT

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2:30 pm - 3:15 pm

Coffee Break & Poster Session #2 

3:15 pm - 3:55 pm

Graduate Student/Postdoctoral Talks (2 x 20 mins)

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Aminative Suzuki–Miyaura Coupling

Paul Onnuch, Liu Lab, Harvard University

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Synthesis of Modified Nucleotides for saRNA Applications: Electrochemical Installation of Fluorinated Motifs on Purines and Pyrimidines

Kaitlyn Corazzata, Schaus Lab, Boston University

3:55 pm - 4:55 pm

Industrial Keynote

Think Biologically, Act Chemically

Matthew LaMarche, Head of Integrated Drug Discovery, Sanofi

4:55 pm - 5:00 pm

Closing Remarks

Jason Tedrow, Head of Process Chemistry, Sanofi

5:00 pm - 6:30 pm

Networking Reception

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